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Aldactone (spironolactone) is indicated in the management of Establishing the diagnosis of primary hyperaldosteronism by therapeutic trial. Short-term preoperative treatment of patients with primary hyperaldosteronism.
Long-term maintenance therapy for patients with discrete aldosterone-producing adrenal adenomas who are judged to be poor operative risks or who decline surgery.Long-term maintenance therapy for patients with bilateral micro or macronodular adrenal hyperplasia (idiopathic hyperaldosteronism).
For the management of edema and sodium retention when the patient is only partially responsive to or is intolerant of other therapeutic measures. Aldactone is also indicated for patients with congestive heart failure taking digitalis when other therapies are considered inappropriate.
For nephrotic patients, when treatment of the underlying disease, restriction of fluid and sodium intake and the use of other diuretics do not provide an adequate response.